Preventing juvenile arthritis relapse

preventing juvenile arthritis relapse

Childhood arthritis expert Professor Lucy Wedderburn and her team at UCL have already developed a successful test to predict whether a child’s arthritis will return after their treatment is completed. This allowed doctors to identify high-risk cases and resume treatment to avoid a relapse.

However, the test does not work for all children and for some, arthritis can still return without warning. The team wants to find more ways of predicting relapse, so that more children can be treated preventatively and spared the pain of their arthritis returning.

This would also identify more patients with a low risk of relapse, giving those children the chance to enjoy an active life free from harsh treatments and the worry that their arthritis could return.

“People don’t know there’s such a thing as juvenile arthritis”

Arseni outside, exchanging a high five with a schoolmate

Arseni, 12, is part of a Sparks-funded trial led by Professor Wedderburn Read More ›

Childhood Arthritis Response to Medication Study (CHARMS)

Professor Wedderburn and her team have a great track record of translating research into clinical practice through CHARMS, a five-year programme of research funded by Sparks which was the largest multi-dimensional study of response to treatment in childhood arthritis in the world to date. The hope is that this could be quickly moved into the clinic, even within 2-3 years.

Project overview
Avoiding painful relapse and unnecessary treatment in childhood arthritis
Professor Lucy Wedderburn
UCL Great Ormond Street Institute of Child Health
Grant: £136,870

Help fund more ground-breaking medical research for seriously ill children and their families.